Immune Parameters of Broilers Supplemented with Adsorbents and Quantification Challenged with Mycotoxins

Mycotoxins are one of the most immunosuppressive factors in animal diets. It is important to consider that consumption of certain mycotoxins, at levels that do not cause overt clinical mycotoxicosis, suppresses immune function and decreases resistance to infectious diseases. In this sense, mycotoxin adsorbents that are effective both in combating the damage caused by these metabolites and in protecting and supporting animal health are increasingly essential in the animal nutrition industry. The effect of mycotoxin adsorbents, with different compositions, on immunological parameters in broiler chickens challenged with mycotoxins has been evaluated. We used 300 broilers, distributed in a completely randomized design with four treatments and six replicates. Three mycotoxin adsorbents with different compositions were tested, which were added at 2.5kg/kg, in diets contaminated with 1.0 pp of aflatoxin + 50.0 ppm of fumonisin + 25.0 ppm of DON. Evaluation of a control diet without contamination (T1), contaminated diet + SIM – FIX HP (T2), contaminated diet + adsorbent A (T3), contaminated diet + adsorbent B (T4). On the last day of the experimental period, blood samples were collected from eight birds per treatment for the evaluation of phagocytosis by flow cytometry and the cecal tonsils were collected and the expression of pro-inflammatory interleukin 6 (IL 6) and anti-interleukin 10 determined. -inflammatory (IL 10) through quantification of gene expression by RT-qPCR. In the phagocytosis assay, a significant difference was observed between the control and T4 treatments, with a lower percentage of phagocytic monocytes for treatment 4, which also had the lowest IL-6 (pro-inflammatory) value. In the phagocytosis assay, a significant difference was observed between the control and T4 treatments, with a lower percentage of phagocytic monocytes for treatment 4, which also had the lowest IL-6 value. Among the evaluated adsorbents, YES FIX HP provided the highest average production of IL-10, which suggests a greater balance in the immune response of the animals to the challenge with mycotoxins, possibly contributing to the greater resistance of this group of animals to the main challenges faced in the field. and that require a response from the defense system.

Poultry Summer Challenges

Summer challenges directly influence high-performance poultry production, as the threshold between profit and loss is very close.

Summer Aquaculture Challenges

Summer-Challenges-in-Aquaculture-with-Sidney-Fernandes

As well as winter, summer is also a period that demands attention from aquaculturists. As they are pecilothermic, fish depend on the temperature and environment in which they live.

Summer challenges in dairy farming

The biggest challenge in summer milk production is the heat stress that animals suffer.

Second episode of YesCast addresses the role of immunity for swine profitability

Podcast has the participation of Juliana Bueno and Edson Bordin, Yes specialists, and Losivanio de Lorenzi, President of the Santa Catarina Association of Swine Breeders (ACCS) Always innovating in the way of bringing knowledge to the animal protein sector and being close to its customers and partners, Yes, a company that develops biotechnological solutions for […]

Pig farming in Brazil: production of the future

Our mission, going forward, will really be to produce quality meat. We will have a lot of work in the next decade to face all these new challenges that animal production and human health have brought us.

Transition and postpartum cows

The transition period is critical in milk production. We are aware of the complications that can occur in dairy production on the farm when we do not work properly. What is the transition period? This transition period ranges from 30 days or 21 days for the pre-calving cow to 60 or 90 days post-calving for that cow. It's a period between 90 days and 100 days that I have to be more careful with the cow.

en_USEN